"Forces identified a suspect running towards an (army) post in Silwad, northeast of Ramallah," a spokesperson said.
"The force shot the suspect, resulting in his death."
Silwad, close to the Jewish settlement of Ofra, is under constant stakeout by the Israeli army seeking to prevent attacks on passing settler traffic.
Israel arrests Palestinians 'recruited by Hezbollah' via Facebook
A relative of the dead man identified him as Silwad resident Iyad Hamed, 37, a father of two.
The shooting took place on the road leading past the village to Ofra, his brother-in-law told AFP by phone.
It is the scene of regular clashes between Palestinian stone throwers and troops.
A wave of violence since October has killed 222 Palestinians, 34 Israelis, two Americans, an Eritrean and a Sudanese, according to an AFP tally.
Clashes as Israel destroys Palestinian home over deadly attack
Most of the Palestinians killed were carrying out knife, gun or car-ramming attacks, Israeli authorities say, with the majority of them from the West Bank.
Others have been shot dead during protests and clashes with security forces.
COMMENTS
Comments are moderated and generally will be posted if they are on-topic and not abusive.
For more information, please see our Comments FAQ