Two Turkish soldiers were killed in a gun attack by PKK members in the Derik district of Mardin province in the early morning, it said.
Less than an hour later, four Turkish troops died in a roadside bomb attack by the PKK in the Hakkari province of the extreme southeast of the country, it added.
Militant Kurdish group TAK claims Istanbul bombing
Hundreds of members of the Turkish security forces have been killed by PKK in attacks since a truce collapsed a year ago.
However the government has vowed no let-up in a relentless campaign to wipe the militants from urban centres of Kurdish-dominated southeastern Turkey.
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