Brennan's comments may have an impact on this year's White House race, after Republican frontrunner Donald Trump said he would authorize waterboarding -- which President Barack Obama banned shortly after taking office in 2009 -- and techniques that are "a lot worse" if elected to the highest office in the land.
Trump backs waterboarding and 'a lot more' after Brussels attacks
"I will not agree to carry out some of these tactics and techniques I've heard bandied about because this institution needs to endure," Brennan told NBC News in an interview to be aired later Monday.
"Absolutely, I would not agree to having any CIA officer carrying out waterboarding again," said Brennan.
At the same, a new president could choose to name a new CIA director with the approval of the Senate.
Trump backs waterboarding and 'a lot more' after Brussels attacks
Trump's closest rival conservative Senator Ted Cruz has also said he does not consider the simulated drowning technique to be torture.
Although vowing not to use the method in "widespread" fashion, Cruz has said that as president, he would "use whatever enhanced interrogation methods we could to keep this country safe."
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