Pauline Cafferkey, who voluntarily went to the west African country to treat Ebola patients, was being treated at Glasgow's Queen Elizabeth University Hospital, according to a spokesperson from NHS Greater Glasgow and Clyde.
"Under routine monitoring by the Infectious Diseases Unit, Pauline Cafferkey has been admitted to hospital for further investigations," he said.
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Cafferkey was treated twice at an isolation unit at London's Royal Free Hospital, Britain's only isolation ward for the lethal disease, after suffering an "unusual complication" of her first infection.
Cafferkey was diagnosed with Ebola in December 2014 after returning to Glasgow from Sierra Leone.
She suffered a relapse in October 2015, when the virus caused her to become critically ill with meningitis before she made a full recovery.
"It is very sad to hear that Ms Cafferkey has once again been admitted to hospital," said Derek Gatherer from Lancaster University.
"The meningitis that Ms Cafferkey suffered from at the end of last year is one of the most serious complications of all, as it can be life-threatening.
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"She was unlucky enough to be one of only a handful of patients in whom it has been seen," he added.
The deadliest-ever Ebola outbreak since the virus was identified in central Africa in 1976 has killed 11,316 of the 28,639 people infected since December of 2013, according to the latest WHO figures.
Nearly all the victims have been in Guinea, Liberia and Sierra Leone.
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