More than one million refugees and migrants arrived in the European Union last year and some 3,600 died or went missing, forcing the EU to mull suspending its Schengen open-borders area for up to two years.
The Turkish coast guard was continuing search and rescue efforts where the 17-metre boat carrying at least 120 people sank off the coast of Ayvacik, a town across from the Greek island of Lesvos, the Dogan news agency reported.
"I am afraid the numbers will rise as divers continue the search," Mehmet Unal Sahin, the mayor of Ayvacik, told the CNNTurk news channel by phone.
44 drown in migrant boat sinking as Germany seeks Turkish help
"Local people woke up to the sound of screaming migrants and we have been carrying out rescue work since dawn. We have an 80-kilometre-long coast just across from Lesbos, which is very hard to keep under control."
At least five of those who died were children, Dogan reported, while rescued migrants were hospitalised with hypothermia symptoms. It said the migrants were of Syrian, Afghan and Myanmar origin.
Greek centres
Chancellor Angela Merkel, who opened Germany's borders to Syrians fleeing civil war last summer, is under mounting pressure to halt the inflow.
Merkel told a meeting of a members of her Christian Democratic Union party on Saturday that despite efforts to help refugees, it was important to stress that they had only been given permission for a limited stay.
"We need ...to say to people that this is a temporary residential status and we expect that once there is peace in Syria again, once IS has been defeated in Iraq, that you go back to your home country."
Around 500,000 refugees from the five-year-old war in Syria traveled through Turkey and then risked their lives at sea to reach Greek islands in 2015.
Under pressure from the European Commission about delays, Greece expects to have four of five "hot spot" centers for processing migrants operational in about two weeks, its migration minister said in a newspaper interview published on Saturday.
Twelve migrants drown trying to reach Europe from Turkey
"We are behind schedule on the installation of these hot spots," Greece's Yiannis Mouzalas told Austrian newspaper Der Standard. "Four of the five will be operational from mid-February."
Neighboring Turkey is hosting 2.5 million Syrian refugees. In November it struck a deal with the EU pledging to help stem the flow of migrants to Europe in return for 3 billion euros ($3.3 billion) in financial aid and renewed talks on joining the 28-nation bloc.
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