Addressed to US President Barack Obama, the petition, published on the change.org website, calls for world leaders to commit $1.4 billion at the London conference "to make sure all Syrian children affected by the conflict get an education".
Malala meets Syrian Malala
Britain, Germany and Norway are co-hosting the event on February 4 with the United Nations and Kuwait. A string of world leaders are expected to attend.
They will discuss how to help 13.5 million people who are either vulnerable or displaced inside Syria, as well as 4.2 million people who have fled to neighbouring countries like Jordan and Lebanon.
British Prime Minister David Cameron's office said Wednesday that participating countries would be asked to double the amount of money they are giving to tackle the humanitarian crisis.
World has 'lost humanity' on Syria: Malala
Last year, UN agencies asked for $8.4 billion (7.7 billion euros) from governments worldwide to fund the Syrian aid effort but received only $3.3 billion.
Malala now lives in Birmingham, central England, after being shot by the Taliban in Pakistan 2012 and is expected to take part in the conference, according to the BBC.
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