At least six people, including one policeman, were killed when unidentified men on motorcycles opened fire on a shop on Sirki Road, Express News reported on Sunday.
Four victims were inside the shop whereas the other two victims were passersby, police sources said.
A heavy contingent of police reached the crime scene and cordoned off the area. A search operation is underway.
Bodies of the victims were shifted to Civil Hospital where relatives of the deceased staged protests.
Police sources said that this appeared to be an incident of target killing.
Earlier, two Balochistan Levies personnel were killed in an attack on a check post, and a Hazara community member was shot dead, in separate incidents of violence.