The strikes after midnight targeted an area where displaced Syrians had gathered outside the town of Maaret Misrin in Idlib province, the Syrian Observatory for Human Rights said.
An AFP correspondent saw the bodies of some of the victims wrapped in thick winter blankets at a local hospital.
Turkey shoots down Syrian warplane as fighting escalates
A rescuer carried in the body of a baby girl, her mouth filled with grey debris and her pink pyjamas caked in dust.
At the site of the strikes, two large one-storey out-buildings lay mostly in rubble near green orchards.
The strikes destroyed the poultry farm where the displaced families had been living. Dozens of surviving white chickens picked through the dust, as rescuers operated bulldozers to comb through the debris.
The Observatory said the toll was likely to increase as many wounded were in a critical state.
Moscow-backed regime forces have since December waged a deadly battle against the rebel-dominated Idlib region, causing almost a million people -- mostly women and children -- to flee their homes and shelters.
Even before that offensive, Idlib was home to three million people, around half of them already displaced from other parts of the war-torn country.
The Observatory says it determines what plane carried out a strike according to flight patterns, as well as ammunition and aircraft involved.
The strikes comes as the leaders of Russia and Turkey meet in Moscow to discuss the situation in Idlib, where Ankara backs some rebel groups and has become directly involved in fighting in recent weeks.
Syria's war has killed more than 380,000 people and displaced millions since it started in 2011 with the brutal repression on anti-government protests.
Earlier, A Turkish drone strikes in Syria’s northwestern Idlib province killed 19 government soldiers on Sunday, a war monitor reported, as tensions soared between Damascus and Ankara.
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The 19 died in strikes on a military convoy in the Jabal al-Zawiya area and a base near Maaret al-Numan city, the Syrian Observatory for Human Rights said.
The report came hours after Turkey shot down two Syrian warplanes, in an escalating offensive against the Damascus government in Idlib, where armed groups backed by Ankara pose the biggest obstacle to Damascus seizing back control over all of Syria.
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