The head of Egypt's oil pipelines authority, Abdelmoneim Hafez, said the leak was the work of "thieves" syphoning off oil.
The fire broke out on the pipeline near Itay al-Baroud, a village half-way between Cairo and Alexandria, health ministry spokesperson Khaled Mugahed said in a statement.
The wounded were taken to a nearby hospital, while the blaze was put out and the leak fixed.
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