It will be the first time England have played in Southampton since October 2002 when Sven-Goran Eriksson's side were held to a 2-2 draw by Macedonia.
Both the women's senior team and men's under-21 side have played at St Mary's in recent years and now Gareth Southgate's squad will look to build on their winning start to the Euro qualification campaign.
The Group A fixture scheduled for September 10 would be the first competitive home game England will have played away from Wembley since Old Trafford hosted a qualifier against Macedonia in October 2006.
The FA are keen to take England games around the country as they look to capitalise on the renewed optimism surrounding Southgate's team that reached the World Cup semi-finals last year for the first time since 1990.
The match will also be England's first-ever game with Kosovo since they were affiliated with UEFA and FIFA in 2016.
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