The survey of world leaders and business people addressing top conferences over the last five years shows a "huge gender gap" with 74 per cent of speakers being male, the Open Society Foundations group said.
The report -- titled "An End to Manels", or all-male panels -- comes as campaigns such as #MeToo and #Timesup try to advance the fight for women's rights around the world.
"If you're walking on the street and see four men for every woman you would recognise something is wrong," report co-author Christal Morehouse told a press conference in Brussels.
"But until now, no one has brought this ratio into question for Europe's top conferences."
The worst is the annual Globsec security forum in the Slovak capital Bratislava, with only 12 per cent of female speakers, the study found. Former British premier David Cameron has spoken there in previous years.
That was followed by the Tatra summit, another Globsec-sponsored event, with 14 per cent of women on the podium.
The prestigious Munich Security Conference -- which this year drew British Prime Minister Theresa May and Israeli premier Benjamin Netanyahu -- rounds off the bottom three with 15 per cent of female speakers.
But there is also only one woman for every four male speakers at the Davos World Economic Forum in Switzerland, which saw a keynote speech from US President Donald Trump in January.
Only one averaged equal representation, the Human Dimension Implementation Meeting, run by the OSCE and billed as Europe's largest rights conference.
Britain's Chatham House think-tank had however drastically improved from 28 per cent to 44 per cent within a year of introducing a new selection process.
Morehouse cited Chatham House as an example, saying change can happen "overnight" if all those involved take "conscious" action.
Open Society Foundations, a group founded by US billionaire George Soros, looked at 23 conferences between 2012 and mid-2017, finding that 26 per cent of 12,600 speakers were women and 74 per cent male.
The EU backed the Open Society Foundation's call for an end to "manels."
"It baffles me that event organisers still try to justify their men-only panels by saying 'Oh, we just couldn't find any competent women.' This is simply not a valid argument in 2018," EU Trade Commissioner Cecilia Malmstroem said on Twitter Wednesday.
The #MeToo movement had broken a taboo on discrimination against women, Monika Ladmanova, gender equality advisor for EU Justice Commissioner Vera Jourova, told AFP.
"Now women are speaking up and we need to keep the momentum going," she added.
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