Syrian rescue workers the Civil Defence said that they had carted away at least 100 bodies from the site of Saturday's blast, which hit buses carrying Shi'ite residents as they waited to cross from rebel into government territory in an evacuation deal between warring sides.
Syria's Assad says chemical attack '100 per cent fabrication'
The British-based Observatory said the number was expected to rise.
Those killed were mostly residents of the villages of al-Foua and Kefraya in Idlib province, but included rebel fighters guarding the convoy, the Observatory said.
There was no immediate claim of responsibility for the attack, which pro-Damascus media said was carried out by a suicide car bomber.
Russia vetoes UN draft resolution on Syria gas attack probe
The convoy was carrying at least 5,000 people including civilians and several hundred pro-government fighters, who were granted safe passage out of the two Shi'ite villages which are besieged by rebels.
Under the evacuation deal, more than 2,000 people including rebel fighters were granted safe passage out of Madaya, a town near Damascus besieged by government forces and their allies.
That convoy was waiting at a bus garage in a government-held area on Aleppo's outskirts, a few miles from where the attack took place. Madaya evacuees said they heard the blast.
COMMENTS
Comments are moderated and generally will be posted if they are on-topic and not abusive.
For more information, please see our Comments FAQ