The killings were apparently a murder-suicide, US media reported, citing local law enforcement.
Deputies were still inside the building at Lackland Air Force Base, the Bexar County Sheriff said in a tweet.
We have two dead at Lackland Air Force Base, deputies are still inside the building
— Bexar County Sheriff’s Office (@BexarCoSheriff) April 8, 2016
US Capitol shooting suspect in custody
Schools and daycare centers in the area were also placed on lockdown, according to a Facebook post from Joint Base San Antonio, which includes Lackland as well as other military bases in the area.
The deadliest shooting at a US military base took place in Fort Hood, Texas in 2009, when army psychiatrist Major Nidal Hasan killed 13 people and wounded 42 before being overpowered by police.
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