Chili peppers can battle obesity

Capsaicin present in the vegetable stimulates energy-burning.


Ians February 09, 2015
Capsaicin in chilli peppers may induce browning of white adipose tissue and stimulate thermogenesis to counteract obesity. PHOTO:PUBLICITY

WASHINGTON: There is good news for those who find it hard to resist fatty foods. An ingredient found in chili peppers could help you prevent weight gain after eating a high-fat diet, a study involving an Indian-origin researcher has found.

Capsaicin, being the chief ingredient in chili peppers stimulates energy burning — a dietary supplement could be developed to do away with restriction in calorie intake, the study findings suggest.

“Our group’s laboratory data revealed that dietary capsaicin suppresses high-fat-diet-induced obesity,” explained Vivek Krishnan, a graduate student from the University of Wyoming in the US.

“In our bodies, white fat cells store energy and brown fat cells serve as thermogenic (heat produced by burning fat) machinery to burn stored fat. Eating calorie-rich foods and a lack of physical activity cause an imbalance in metabolism that lead to obesity,” Krishnan explained. The researchers found that 0.01 per cent of capsaicin in a total high-fat diet prevented high-fat-diet-induced weight gain in trials with wild type mice.

Dietary capsaicin may induce browning of white adipose tissue and stimulates thermogenesis to counteract obesity, the researchers noted.

Developing a natural dietary supplement as a strategy to combat obesity can be easily advanced to human clinical trials.

“We envision a nanoparticle-based sustained-release formulation of capsaicin, which is currently under development in our laboratory,” the researchers added.

“In turn, this will advance a novel dietary supplement-based approach to prevent and treat one of the life-threatening diseases, obesity and its associated complications in humans,” they noted.

The findings were presented at Biophysical Society’s 59th annual meeting in Baltimore, Maryland. 

Published in The Express Tribune, February 10th,  2015.

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COMMENTS (1)

vivky | 9 years ago | Reply Interesting study. It has been known that capsicin an active ingredient from chilly has the efficacy against pain but its efficacy against obesity is a newer report. Obesity is the lifestyle diseases and primarily due to sedentary lifestyle. there are several guidelines suggesting that the physically activity and lifestyle modification has the highest impact in these diseases. check this recommendations on www.treatmentguideline.com. If capsicin tablets becomes available and recommended by the guidelines with appropriate dose can be used to treat obesity but there is a need of more data on it.
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